Our latest study on dynamics of remodeler activity is out in Nature Genetics. We use inhibition of SWI/SNF by a small molecule in mouse embryonic stem cells to study dynamics of chromatin opening, nucleosome remodeling and remodeler-mediated binding of transcription factors. This was a rewarding and fruitful collaboration with NIBR colleagues, highlighting how chemical inhibition can shed light on chromatin regulation.
Press release: https://www.fmi.ch/news-events/articles/news.html?news=490
Article: https://www.nature.com/articles/s41588-020-00768-w
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