2024
2023
2022
Systematic assessment of ISWI subunits shows that NURF creates local accessibility for CTCF
Mario Iurlaro, Francesca Masoni, Christiane Wirbelauer, Murat Iskar, Lukas Burger, Dirk Schübeler
Nature genetics
Cooperation between bHLH transcription factors and histones for DNA access
Alicia K Michael, Lisa Stoos, Priya Crosby, Nikolas Eggers, Xinyu Y Nie, Kristina Makasheva, Martina Minnich, Kelly L Healy, Joscha Weiss, Georg Kempf, Simone Cavadini, Lukas Kater, Jan Seebacher, Luca Vecchia, Deyasini Chakraborty, Luke Isbel, Ralph S Grand, Florian Andersch, Jennifer L Fribourgh, Dirk Schübeler, Johannes Zuber, Andrew C Liu, Peter B Becker, Beat Fierz, Carrie L Partch, Jerome S Menet, Nicolas H Thomä
Nature 619, 385–393
Inês AM Barbosa, Rajaraman Gopalakrishnan, Samuele Mercan, Thanos P Mourikis, Typhaine Martin, Simon Wengert, Caibin Sheng, Fei Ji, Rui Lopes, Judith Knehr, Marc Altorfer, Alicia Lindeman, Carsten Russ, Ulrike Naumann, Javad Golji, Kathleen Sprouffske, Louise Barys, Luca Tordella, Dirk Schübeler, Tobias Schmelzle, Giorgio G Galli
Nature communications 14, 3907
Readout of histone methylation by Trim24 locally restricts chromatin opening by p53
Luke Isbel, Murat Iskar, Sevi Durdu, Joscha Weiss, Ralph S Grand, Eric Hietter-Pfeiffer, Zuzanna Kozicka, Alicia K Michael, Lukas Burger, Nicolas H Thomä, Dirk Schübeler
Nature Structural & Molecular Biology 30, 948–957
Evidence that direct inhibition of transcription factor binding is the prevailing mode of gene and repeat repression by DNA methylation
S Kalusha, S Domcke, C Wirbelauer, MB Stadler, S Durdu, L Burger, D Schübeler
Nature Genetics, 54 (12), 1895–1906
DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions
S Butz, N Schmolka, ID Karemaker, R Villaseñor, I Schwarz, S Domcke, ECH Uijttewaal, J Jude, F Lienert, AR Krebs, NP de Wagenaar, X Bao, J Zuber, U Elling, D Schübeler, T Baubec
Nature Genetics 54 (11), 1702-1710
Generating specificity in genome regulation through transcription factor sensitivity to chromatin
L Isbel, RS Grand, D Schübeler
Nature Reviews Genetics, 23, 728–740
monaLisa: an R/Bioconductor package for identifying regulatory motifs
D Machlab, L Burger, C Soneson, FM Rijli, D Schübeler, MB Stadler
Bioinformatics 38 (9), 2624-2625
2021
BANP opens chromatin and activates CpG-island-regulated genes
RS Grand*, L Burger*, C Gräwe, AK Michael, L Isbel, D Hess, L Hoerner, V Iesmantavicius, S Durdu, M Pregnolato, AR Krebs, SA Smallwood, N Thomä, M Vermeulen, D Schübeler
Nature 596 (7870), 133-137
Systematic dissection of transcriptional regulatory networks by genome-scale and single-cell CRISPR screens
R Lopes, K Sprouffske, C Sheng, ECH Uijttewaal, AE Wesdorp, J Dahinden, S Wengert, J Diaz-Miyar, U Yildiz, M Bleu, V Apfel, F Mermet-Meillon, R Krese, M Eder, AV Olsen, P Hoppe, J Knehr, W Carbone, R Cuttat, A Waldt, M Altorfer, U Naumann, J Weischenfeldt, A DeWeck, A Kauffmann, G Roma, D Schübeler, GG Galli
Science Advances 7 (27), eabf5733
Mammalian SWI/SNF continuously restores local accessibility to chromatin
M Iurlaro, MB Stadler, F Masoni, Z Jagani, GG Galli, D Schübeler
Nature Genetics, 53 (3), 279–287.
2020
A genome-scale map of DNA methylation turnover identifies site-specific dependencies of DNMT and TET activity
PA Ginno*, D Gaidatzis*, A Feldmann*, L Hoerner, D Imanci, L Burger, F Zilbermann, AHFM Peters, F Edenhofer, SA Smallwood, AR Krebs, D Schübeler
Nature Communications, 11(1):2680
Mechanisms of OCT4-SOX2 motif readout on nucleosomes
AK Michael*, RS Grand*, L Isbel*, S Cavadini, Z Kozicka, G Kempf, RD Bunker, AD Schenk, A Graff-Meyer, GR Pathare, J Weiss, S Matsumoto, L Burger, D Schübeler, NH Thomä
Science, 368, 6498, 1460-1465
Molecular Co-occupancy Identifies Transcription Factor Binding Cooperativity In Vivo
C Sönmezer, R Kleinendorst, D Imanci, G Barzaghi, L Villacorta, D Schübeler, V Benes, N Molina, AR Krebs
Molecular Cell, 81 (2), 255-267. e6
2019
Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans
J Juettner, A Szabo, B Gross-Scherf, RK Morikawa, SB Rompani, P Hantz, T Szikra, F Esposti, CS Cowan, A Bharioke, CP Patino-Alvarez, Ö Keles, A Kusnyerik, T Azoulay, D Hartl, AR Krebs, D Schübeler, RI Hajdu, A Lukats, J Nemeth, ZZ Nagy, K-C Wu, R-H Wu, L Xiang, X-L Fang, Z-B Jin, D Goldblum, PW Hasler, HPN Scholl, J Krol, B Roska
Nature Neuroscience, 22 (8), 1345-1356
DNA damage detection in nucleosomes involves DNA register shifting
S Matsumoto, S Cavadini, RD Bunker, RS Grand, A Potenza, J Rabl, J Yamamoto, AD Schenk, D Schübeler, S Iwai, K Sugasawa, H Kurumizaka, NH Thomä
Nature, 571, 79–84
Mammalian ISWI and SWI/SNF selectively mediate binding of distinct transcription factors
D Barisic*, MB Stadler*, M Iurlaro*, D Schübeler
Nature, 569 (7754), 136–140
CG dinucleotides enhance promoter activity independent of DNA methylation
D Hartl, AR Krebs, RS Grand, T Baubec, L Isbel, C Wirbelauer, L Burger and D Schubeler
Genome Research 29, 554–563
2018
Non-mendelian Inheritance in Mammals Is Highly Constrained
L Isbel, D Schübeler
Cell 175 (5), 1179-1181
Cell cycle-resolved chromatin proteomics reveals the extent of mitotic preservation of the genomic regulatory landscape
PA Ginno, L Burger, J Seebacher, V Iesmantavicius, D Schübeler
Nature Communications 9 (1), 4048
2017
Binding of high mobility group A proteins to the mammalian genome occurs as a function of AT-content
DF Colombo*, L Burger*, T Baubec, D Schübeler
PLoS Genetics 13 (12), e1007102
Evidence for Converging DNA Methylation Pathways in Placenta and Cancer
MC Lorincz, D Schübeler
Developmental Cell 43 (3), 257-258
Cis-regulatory landscapes of four cell types of the retina
D Hartl*, AR Krebs*, J Jüttner*, B Roska, D Schübeler
Nucleic Acids Research 45 (20), 11607-11621
Genome-wide single-molecule footprinting reveals high RNA polymerase II turnover at paused promoters
AR Krebs, D Imanci, L Hoerner, D Gaidatzis, L Burger, D Schübeler
Molecular Cell 67 (3), 411-422. e4
Multidimensional pooled shRNA screens in human THP-1 cells identify candidate modulators of macrophage polarization
E Surdziel, I Clay, F Nigsch, A Thiemeyer, C Allard, G Hoffman, JS Reece-Hoyes, T Phadke, R Gambert, CG Keller, M-G Ludwig, B Baumgarten, M Frederiksen, D Schübeler, K Seuwen, T Bouwmeester, BD Fodor
PloS One 12 (8), e0183679
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Y Yin, E Morgunova, A Jolma, E Kaasinen, B Sahu, S Khund-Sayeed, Pratyush K Das, T Kivioja, K Dave, F Zhong, KR Nitta, M Taipale, A Popov, PA Ginno, S Domcke, J Yan, D Schübeler, C Vinson, J Taipale
Science 356 (6337), eaaj2239
2016
The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery
HG Stunnenberg and The International Human Epigenome Consortium
Cell 167 (5), 1145-1149
Pioneering activity of the C-terminal domain of EBF1 shapes the chromatin landscape for B cell programming
S Boller, S Ramamoorthy, D Akbas, R Nechanitzky, L Burger, R Murr, D Schübeler, R Grosschedl
Immunity 44 (3), 527-541
2015
Competition between DNA methylation and transcription factors determines binding of NRF1
S Domcke*, AF Bardet*, PA Ginno, D Hartl, L Burger, D Schübeler
Nature 528 (7583), 575
Loss of Ezh2 promotes a midbrain-to-forebrain identity switch by direct gene derepression and Wnt-dependent regulation
M Zemke, K Draganova, A Klug, A Schöler, L Zurkirchen, MHP Gay, P Cheng, H Koseki, T Valenta, D Schübeler, K Basler, L Sommer
BMC biology 13 (1), 103
Aging-dependent demethylation of regulatory elements correlates with chromatin state and improved β cell function
D Avrahami, C Li, J Zhang, J Schug, R Avrahami, S Rao, MB Stadler, L Burger, D Schübeler, B Glaser, KH Kaestner
Cell Metabolism 22 (4), 619-632
YAP1 exerts its transcriptional control via TEAD-mediated activation of enhancers
C Stein*, AF Bardet*, G Roma, S Bergling, I Clay, A Ruchti, C Agarinis, T Schmelzle, T Bouwmeester, D Schuebeler*, A Bauer*
PLoS Genetics 11 (8), e1005465
Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
T Baubec, DF Colombo, C Wirbelauer, J Schmidt, L Burger, AR Krebs, A Akalin, D Schübeler
Nature 520 (7546), 243
ESCI award lecture: regulation, function and biomarker potential of DNA methylation
D Schübeler
European journal of clinical investigation 45 (3), 288-293
Function and information content of DNA methylation
D Schübeler
Nature 517 (7534), 321
2014
Genomation: a toolkit to summarize, annotate and visualize genomic intervals
A Akalin*, V Franke, K Vlahoviček, CE Mason*, D Schübeler*
Bioinformatics 31 (7), 1127-1129
Dynamic DNA methylation orchestrates cardiomyocyte development, maturation and disease
R Gilsbach, S Preissl, BA Grüning, T Schnick, L Burger, V Benes, A Würch, U Bönisch, S Günther, R Backofen, BK Fleischmann, D Schübeler, L Hein
Nature Communications 5, 5288
High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions
AR Krebs, S Dessus-Babus, L Burger, D Schübeler
eLife 3, e04094
Short sequences can efficiently recruit histone H3 lysine 27 trimethylation in the absence of enhancer activity and DNA methylation
P Jermann, L Hoerner, L Burger, D Schübeler
Proceedings of the National Academy of Sciences 111 (33), E3415-E3421
Genomic patterns and context specific interpretation of DNA methylation
T Baubec, D Schübeler
Current opinion in genetics & development 25, 85-92
Acetylation of histone H3 at lysine 64 regulates nucleosome dynamics and facilitates transcription
V Di Cerbo, F Mohn, DP Ryan, E Montellier, S Kacem, P Tropberger, E Kallis, M Holzner, L Hoerner, A Feldmann, FM Richter, AJ Bannister, G Mittler, J Michaelis, S Khochbin, R Feil, D Schuebeler, T Owen-Hughes, S Daujat, R Schneider
eLife 3, e01632
DNA methylation is required for the control of stem cell differentiation in the small intestine
KL Sheaffer, R Kim, R Aoki, EN Elliott, J Schug, L Burger, D Schübeler, KH Kaestner
Genes & Development 28 (6), 652-664
Ezh2 is required for neural crest-derived cartilage and bone formation
D Schwarz, S Varum, M Zemke, A Schöler, A Baggiolini, K Draganova, H Koseki, D Schübeler, L Sommer
Development 141 (4), 867-877
DNA sequence explains seemingly disordered methylation levels in partially methylated domains of Mammalian genomes
D Gaidatzis, L Burger, R Murr, A Lerch, S Dessus-Babus, D Schübeler, MB Stadler
PLoS Genetics 10 (2), e1004143
2013
Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions
A Feldmann, R Ivanek, R Murr, D Gaidatzis, L Burger, D Schübeler
PLoS Genetics 9 (12), e1003994
Gene regulation and priming by topoisomerase IIα in embryonic stem cells
S Thakurela, A Garding, J Jung, D Schübeler, L Burger, VK Tiwari
Nature Communications 4, ncomms3478
Twisting chromatin in stem cells
P Ginno, D Schübeler
The EMBO Journal 32 (17), 2304-2306
Identification of active regulatory regions from DNA methylation data
L Burger, D Gaidatzis, D Schübeler, MB Stadler
Nucleic Acids Research 41 (16), e155-e155
Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa
S Erkek, M Hisano, CY Liang, M Gill, R Murr, J Dieker, D Schübeler, J Van Der Vlag, MB Stadler, AHFM Peters
Nature Structural & Molecular Biology 20 (7), 8681842013
Sox4 is a master regulator of epithelial-mesenchymal transition by controlling Ezh2 expression and epigenetic reprogramming
N Tiwari, VK Tiwari, L Waldmeier, PJ Balwierz, P Arnold, M Pachkov, N Meyer-Schaller, D Schübeler, E van Nimwegen, G Christofori
Cancer Cell 23 (6), 768-783
A systematic comparison of enzymatic activity and protein interaction analysis of the KDM3 histone demethylase subfamily
M Brauchle, Z Yao, R Arora, I Clay, B Inverardi, B Gerrits, J Voshol, A Bauer, D Schuebeler, A Bouwmeester, H Ruffner, S Thigale
PLoS One 8 (4), e60549
Methylation-dependent and-independent genomic targeting principles of the MBD protein family
T Baubec, R Ivánek, F Lienert, D Schübeler
Cell 153 (2), 480-492
Protein complex interactor analysis and differential activity of KDM3 subfamily members towards H3K9 methylation
M Brauchle, Z Yao, R Arora, S Thigale, I Clay, B Inverardi, J Fletcher, P Taslimi, MG Acker, B Gerrits, J Voshol, A Bauer, D Schübeler, T Bouwmeester, H Ruffner
PLoS One 8 (4), e60549
Modeling of epigenome dynamics identifies transcription factors that mediate Polycomb targeting
P Arnold*, A Schöler*, M Pachkov, PJ Balwierz, H Jørgensen, MB Stadler, E van Nimwegen*, D Schübeler*
Genome Research 23 (1), 60-73
2012
Epigenetic islands in a genetic ocean
D Schübeler
Science 338 (6108), 756-757
Tracking the evolution of cancer methylomes
AR Krebs, D Schübeler
Nature Genetics 44 (11), 1173
Identification of Dlk1-Dio3 Imprinted Gene Cluster Noncoding RNAs as Novel Candidate Biomarkers for Liver Tumor Promotion
H Lempiäinen, P Couttet, F Bolognani, A Müller, V Dubost, R Luisier, A del Rio-Espinola, V Vitry, EB Unterberger, JP Thomson, F Treindl, U Metzger, C Wrzodek, F Hahne, T Zollinger, S Brasa, M Kalteis, M Marcellin, F Giudicelli, A Braeuning, L Morawiec, N Zamurovic, U Längle, N Scheer, D Schübeler, J Goodman, S-D Chibout, J Marlowe, D Theil, DJ Heard, O Grenet, A Zell, MF Templin, RR Meehan, RC Wolf, CR Elcombe, M Schwarz, P Moulin, R Terranova, JG Moggs
Toxicological Sciences 131 (2), 375-386
Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome
JP Thomson, H Lempiäinen, JA Hackett, CE Nestor, A Müller, F Bolognani, EJ Oakeley, D Schübeler, R Terranova, D Reinhardt, JG Moggs, RR Meehan
Genome Biology 13 (10), R93
Target genes of Topoisomerase IIβ regulate neuronal survival and are defined by their chromatin state
VK Tiwari, L Burger, V Nikoletopoulou, R Deogracias, S Thakurela, C Wirbelauer, J Kaut, R Terranova, L Hoerner, C Mielke, F Boege, R Murr, AHFM Peters, Y-A Barde, D Schübeler
Proceedings of the National Academy of Sciences, 201119798
BLUEPRINT to decode the epigenetic signature written in blood
D Adams et al.
Nature Biotechnology 30 (3), 224
Chromatin measurements reveal contributions of synthesis and decay to steady‐state mRNA levels
SC Tippmann, R Ivanek, D Gaidatzis, A Schöler, L Hoerner, E Van Nimwegen, PF Stadler, MB Stadler, D Schübeler
Molecular Systems Biology 8 (1), 593
A chromatin-modifying function of JNK during stem cell differentiation
VK Tiwari, MB Stadler, C Wirbelauer, R Paro, D Schübeler, C Beisel
Nature Genetics 44 (1), 94
2011
DNA-binding factors shape the mouse methylome at distal regulatory regions
MB Stadler*, R Murr*, L Burger*, R Ivanek, F Lienert, A Schöler, E van Nimwegen, C Wirbelauer, EJ Oakeley, D Gaidatzis, VK Tiwari, D Schübeler
Nature 480, 490–495 (2011)
Identification of genetic elements that autonomously determine DNA methylation states
F Lienert, C Wirbelauer, I Som, A Dean, F Mohn, D Schübeler
Nature Genetics 43 (11), 1091
Determinants and dynamics of genome accessibility
O Bell, VK Tiwari, NH Thomä, D Schübeler
Nature Reviews Genetics 12 (8), 554
Genomic prevalence of heterochromatic H3K9me2 and transcription do not discriminate pluripotent from terminally differentiated cells
F Lienert, F Mohn, VK Tiwari, T Baubec, TC Roloff, D Gaidatzis, MB Stadler, D Schübeler
PLoS Genetics 7 (6), e1002090
Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice
H Lempiäinen, A Müller, S Brasa, SS Teo, TC Roloff, L Morawiec, N Zamurovic, A Vicart, E Funhoff, P Couttet, D Schübeler, O Grenet, J Marlowe, J Moggs, R Terranova
PLoS One 6 (3), e18216
2010
Targets and dynamics of promoter DNA methylation during early mouse development
J Borgel, S Guibert, Y Li, H Chiba, D Schübeler, H Sasaki, T Forné, M Weber
Nature Genetics 42 (12), 1093
Chromatin in multicolor
D Schübeler
Cell 143 (2), 183-184
Tackling the epigenome: challenges and opportunities for collaboration
JS Satterlee, D Schübeler, HH Ng
Nature Biotechnology 28 (10), 1039
Accessibility of the Drosophila genome discriminates PcG repression, H4K16 acetylation and replication timing
O Bell, M Schwaiger, EJ Oakeley, F Lienert, C Beisel, MB Stadler, D Schübeler
Nature Structural & Molecular Biology 17 (7), 894
Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa
U Brykczynska, M Hisano, S Erkek, L Ramos, EJ Oakeley, TC Roloff, C Beisel, D Schübeler, MB Stadler, AHFM Peters
Nature Structural & Molecular Biology 17 (6), 679
Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs
J Krol, V Busskamp, I Markiewicz, MB Stadler, S Ribi, J Richter, J Duebel, S Bicker, HJ Fehling, D Schübeler, TG Oertner, G Schratt, M Bibel, B Roska, W Filipowicz
Cell 141 (4), 618-631
Heterochromatin protein 1 (HP1) modulates replication timing of the Drosophila genome
M Schwaiger, H Kohler, EJ Oakeley, MB Stadler, D Schübeler
Genome Research 20, 771–780
2009
Epigenomics: methylation matters
D Schübeler
Nature 462 (7271), 296
Chromatin: sub out the replacement
O Bell, D Schübeler
Current Biology 19 (14), R545-R547
H3K64 trimethylation marks heterochromatin and is dynamically remodeled during developmental reprogramming
S Daujat, T Weiss, F Mohn, UC Lange, C Ziegler-Birling, U Zeissler, M Lappe, D Schübeler, M-E Torres-Padilla, R Schneider
Nature Structural & Molecular Biology 16 (7), 777
Relics of repeat-induced point mutation direct heterochromatin formation in Neurospora crassa
ZA Lewis, S Honda, TK Khlafallah, JK Jeffress, M Freitag, F Mohn, D Schübeler, EU Selker
Genome Research 19 (3), 427-437
Chromatin state marks cell-type-and gender-specific replication of the Drosophila genome
M Schwaiger, MB Stadler, O Bell, H Kohler, EJ Oakeley, D Schübeler
Genes & Development 23 (5), 589-601
Genetics and epigenetics: stability and plasticity during cellular differentiation
F Mohn, D Schübeler
Trends in Genetics 25 (3), 129-136
2008
PcG proteins, DNA methylation, and gene repression by chromatin looping
VK Tiwari, KM McGarvey, JDF Licchesi, JE Ohm, JG Herman, D Schübeler, SB Baylin
PLoS Biology 6 (12), e306
DNA methylation in ES cells requires the lysine methyltransferase G9a but not its catalytic activity
KB Dong, IA Maksakova, F Mohn, D Leung, R Appanah, S Lee, HW Yang, LL Lam, DL Mager, D Schübeler, M Tachibana, Y Shinkai, MC Lorincz
The EMBO Journal 27 (20), 2691-2701
Global reorganization of replication domains during embryonic stem cell differentiation
I Hiratani, T Ryba, M Itoh, T Yokochi, M Schwaiger, CW Chang, Y Lyou, TM Townes, D Schübeler, DM Gilbert
PLoS Biology 6 (10), e245
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
F Mohn, M Weber, M Rebhan, TC Roloff, J Richter, MB Stadler, M Bibel, D Schübeler
Molecular Cell 30 (6), 755-766
Transcription-coupled methylation of histone H3 at lysine 36 regulates dosage compensation by enhancing recruitment of the MSL complex in Drosophila melanogaster
O Bell, T Conrad, J Kind, C Wirbelauer, A Akhtar, D Schübeler
Molecular and Cellular Biology 28 (10), 3401-3409
2007
Localized H3K36 methylation states define histone H4K16 acetylation during transcriptional elongation in Drosophila
O Bell, C Wirbelauer, M Hild, AND Scharf, M Schwaiger, DM MacAlpine, F Zilbermann, F Van Leeuwen, SP Bell, A Imhof, D Garza, AHFM Peters, D Schübeler
The EMBO Journal 26 (24), 4974-4984
RNA polymerase II: just stopping by
MC Lorincz, D Schübeler
Cell 130 (1), 16-18
Genomic patterns of DNA methylation: targets and function of an epigenetic mark
M Weber, D Schübeler
Current opinion in cell biology 19 (3), 273-280
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
M Weber, I Hellmann, MB Stadler, L Ramos, S Pääbo, M Rebhan, D Schübeler
Nature Genetics 39 (4), 457
Enhancing genome annotation with chromatin
D Schübeler
Nature Genetics 39 (3), 284
2006
Dosage compensation in high resolution: global up-regulation through local recruitment
D Schübeler
Genes & Development 20 (7), 749-753
A question of timing: emerging links between transcription and replication
M Schwaiger, D Schübeler
Current opinion in genetics & development 16 (2), 177-183
Epigenomics: Mapping the methylome
IM Wilson, JJ Davies, M Weber, CJ Brown, CE Alvarez, C MacAulay, D Schübeler,WL Lam
Cell Cycle 5 (2), 155-158
2005
Defining epigenetic states through chromatin and RNA
D Schübeler, SCR Elgin
Nature Genetics 37 (9), 917
A new map for navigating the yeast epigenome
D Schübeler, BM Turner
Cell 122 (4), 489-492
Variant histone H3. 3 is deposited at sites of nucleosomal displacement throughout transcribed genes while active histone modifications show a promoter-proximal bias
C Wirbelauer, O Bell, D Schübeler
Genes & Development 19 (15), 1761-1766
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
M Weber, JJ Davies, D Wittig, EJ Oakeley, M Haase, WL Lam, D Schübeler
Nature Genetics 37 (8), 853
Foreword: From genetic diversity to chromosomal biology: an array of tasks beyond expression
D Schübeler
Chromosome Research 13 (3), 223-224
Methylation of histones: playing memory with DNA
AHFM Peters, D Schübeler
Current opinion in cell biology 17 (2), 230-238
2004
DNA replication-timing analysis of human chromosome 22 at high resolution and different developmental states
EJ White, O Emanuelsson, D Scalzo, T Royce, S Kosak, EJ Oakeley, S Weissman, M Gerstein, M Groudine, M Snyder, D Schübeler
Proceedings of the National Academy of Sciences 101 (51), 17771-17776
The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote
D Schübeler, DM MacAlpine, D Scalzo, C Wirbelauer, C Kooperberg, F Van Leeuwen, DE Gottschling, LP O'Neill, BM Turner, J Delrow, SP Bell, M Groudine
Genes & Development 18 (11), 1263-1271
* = equal contribution